This weeks optimal lineup for DraftKings includes players from all Sunday and Monday nights games. Use our week 10 optimal lineup in 50/50 and double up cash games, not guaranteed prize pool tournaments. Our optimal lineup tool by default creates lineups that are best suited for 50/50 games however you can customize the tool by stacking and locking certain key positions to create your own GPP lineups. Locking in and upper tier RB and QB then stacking your QB with at least one of his WR's is an example of how to create an optimal lineup for GPP.
Here's The Week 10 Optimal Lineup For Fanduel
| Q | Matt Ryan | at TB | 27 | 25.266 | 6300 |
| R | LeSean McCoy | vs. Car | 29 | 18.52 | 5600 |
| R | Bobby Rainey | vs. Atl | 32 | 15.09 | 4400 |
| T | Mychal Rivera | vs. Den | 26 | 13.1 | 3800 |
| W | Demaryius Thomas | at Oak | 7 | 26.73 | 8500 |
| W | Kelvin Benjamin | at Phi | 28 | 16.85 | 4200 |
| W | Percy Harvin | vs. Pit | 17 | 16.02 | 5300 |
| F | Antonio Brown | at NYJ | 20 | 28.29 | 8700 |
| D | Baltimore Ravens | vs. Ten | NA | 12.7 | 3200 |
This is the lineup tools default lineup. I didn't lock or remove any players. You could probably get more value out of skill positions by locking in the cheapest defense this week that our algorithm selected, which is the New Orleans Saints. Yes, you heard me right, the New Orleans Saints. In the last 3 weeks the Saints defense has been very useable for Fantasy purposes, see below.
| Opp | Int | FumR | Sack | Pnts Allowed |
| @Det | 2 | 0 | 3 | 24 |
| GB | 2 | 1 | 4 | 23 |
| @Car | 1 | 1 | 4 | 10 |
The 49'ers have given up 29 combined Fantasy Points to opposing defenses in their last two games. The Saints are red hot right now and the dome will be rocking against a much hated 49'ers team.
Good luck this week!
