Things continue to get worse for the Bills’ defense. DE Mark Anderson will miss “significant time†with a knee injury, GM Buddy Nix said Wednesday. “We don’t know exactly how long it’ll be yet. We should know by tonight or first thing in the morning how long it’ll be, but we do know that he’s out right now,†Nix told the team’s website. Anderson, who injured the knee in Sunday’s loss to the 49ers, has 12 tackles and one sack this season. Chris Kelsay will likely start in his place. Source: Pro Football Weekly