I'll be back Thursday to update my week 16 team defense rankings. The rankings below probably won't move much but the news cycle is pretty fast and furious and I have around 10 key injuries that I'm not sure about yet. I'm locking in the top 7 below for sure. I'm thinking any bumps up will only be for streaming considerations.
| Rank | Team DST | Opp |
| 1 | Los Angeles | at ARI |
| 2 | Chicago | at SF |
| 3 | Tennessee | vs. WAS |
| 4 | Minnesota | at DET |
| 5 | Denver | at OAK |
| 6 | New England | vs. BUF |
| 7 | Dallas | vs. TB |
| 8 | Houston | at PHI |
| 9 | Miami | vs. JAC |
| 10 | Indianapolis | vs. NYG |
| 11 | Jacksonville | at MIA |
| 12 | Cleveland | vs. CIN |
| 13 | Baltimore | at LAC |
| 14 | Los Angeles | vs. BAL |
| 15 | Green Bay | at NYJ |
| 16 | New Orleans | vs. PIT |
| 17 | Atlanta | at CAR |
| 18 | Washington | at TEN |
| 19 | Carolina | vs. ATL |
| 20 | Philadelphia | vs. HOU |
| 21 | Buffalo | at NE |
| 22 | San Francisco | vs. CHI |
| 23 | Kansas City | at SEA |
| 24 | Cincinnati | at CLE |
| 25 | New York Jets | vs. GB |
| 26 | Oakland | vs. DEN |
| 27 | Detroit | vs. MIN |
| 28 | Seattle | vs. KC |
| 29 | New York Giants | at IND |
| 30 | Pittsburgh | at NO |
| 31 | Tampa Bay | at DAL |
| 32 | Arizona | vs. LAR |
