Projecting ownership is pretty easy thanks to some sites still publishing ownership data from their Thursday match-ups. Since prices vary from site to site these are not perfect ownership projections. However, I've changed the ownership percentage into a ranking so no one gets confused. A ranking of 1 means that player was the most owned. Here's the NFL optimal lineups for week 5.
| Quarterback | Rank | Upside/Target |
| Ben Roethlisberger | 1 | x |
| Derek Carr | 2 | x |
| Brian Hoyer | 3 | |
| Tom Brady | 4 | |
| Drew Stanton | 5 | |
| Carson Wentz | 6 | |
| Eli Manning | 7 | x |
| Ryan Fitzpatrick | 8 | |
| Aaron Rodgers | 9 | x |
| Philip Rivers | 10 | |
| Joe Flacco | 11 | x |
| Dak Prescott | 12 | |
| Andrew Luck | 13 | |
| Jameis Winston | 14 | |
| Derek Anderson | 15 | |
| Andy Dalton | 16 | |
| Kirk Cousins | 17 | |
| Ryan Tannehill | 18 | |
| Blaine Gabbert | 19 | |
| Matt Ryan | 20 | |
| Sam Bradford | 21 | |
| Matthew Stafford | 22 | |
| Cam Newton | 23 | x |
| Cody Kessler | 24 | |
| Tyrod Taylor | 25 | |
| Paxton Lynch | 26 | |
| Running Back | Rank | Upside/Target |
| Jordan Howard | 1 | x |
| David Johnson | 2 | x |
| Jerick McKinnon | 3 | x |
| DeAndre Washington | 4 | x |
| Melvin Gordon | 5 | x |
| DeMarco Murray | 6 | |
| C.J. Anderson | 7 | x |
| Le'Veon Bell | 8 | |
| Theo Riddick | 9 | |
| Carlos Hyde | 10 | |
| Terrance West | 11 | x |
| LeSean McCoy | 12 | |
| LeGarrette Blount | 13 | x |
| Todd Gurley | 14 | |
| Ezekiel Elliott | 15 | |
| Frank Gore | 16 | |
| Devonta Freeman | 17 | x |
| James White | 18 | |
| Lamar Miller | 19 | |
| Bilal Powell | 20 | x |
| Duke Johnson | 21 | x |
| Eddie Lacy | 22 | |
| Bobby Rainy | 23 | |
| Ryan Mathews | 24 | |
| Isaiah Crowell | 25 | |
| Darren Sproles | 26 | |
| Fozzy Whittaker | 27 | |
| Latavius Murray | 28 | |
| Wendell Smallwood | 29 | |
| Matt Jones | 30 | |
| Jeremy Hill | 31 | |
| Giovani Bernard | 32 | |
| Jalen Richard | 33 | |
| Matt Forte | 34 | |
| Charles Sims | 35 | |
| Kenneth Dixon | 36 | |
| Jay Ajayi | 37 | |
| Wide Receiver | Rank | Upside/Target |
| Antonio Brown | 1 | x |
| Brandon Marshall | 2 | x |
| Jordy Nelson | 3 | x |
| Steve Smith | 4 | |
| Mike Evans | 5 | |
| Sammie Coates | 6 | x |
| Amari Cooper | 7 | |
| Odell Beckham | 8 | x |
| T.Y. Hilton | 9 | x |
| Michael Crabtree | 10 | |
| Quincy Enunwa | 11 | x |
| Emmanuel Sanders | 12 | |
| Julian Edelman | 13 | |
| Jordan Matthews | 14 | |
| Jarvis Landry | 15 | |
| Dontrelle Inman | 16 | |
| Kelvin Benjamin | 17 | |
| Eddie Royal | 18 | |
| Alshon Jeffery | 19 | |
| A.J. Green | 20 | x |
| Tyrell Williams | 21 | |
| Brice Butler | 22 | |
| Marvin Jones | 23 | |
| John Brown | 24 | |
| Travis Benjamin | 25 | x |
| Terrelle Pryor | 26 | |
| Cameron Meredith | 27 | |
| Robert Woods | 28 | |
| Sterling Shepard | 29 | x |
| DeVante Parker | 30 | |
| Randall Cobb | 31 | |
| Chris Hogan | 32 | |
| Larry Fitzgerald | 33 | |
| Jamison Crowder | 34 | |
| DeSean Jackson | 35 | |
| Demaryius Thomas | 36 | |
| Mike Wallace | 37 | |
| Kenny Stills | 38 | |
| Stefon Diggs | 39 | |
| Anquan Boldin | 40 | |
| Tajae Sharpe | 41 | |
| Terrance Williams | 42 | |
| Brian Quick | 43 | |
| Will Fuller | 44 | |
| Golden Tate | 45 | |
| Danny Amendola | 46 | |
| Julio Jones | 47 | |
| Jeremy Kerley | 48 | |
| Braxton Miller | 49 | |
| Seth Roberts | 50 | |
| Victor Cruz | 51 | |
| Michael Floyd | 52 | |
| Phillip Dorsett | 53 | |
| Nelson Agholor | 54 | |
| Cole Beasley | 55 | |
| Tight End | Rank | Upside/Target |
| Zach Ertz | 1 | x |
| Greg Olsen | 2 | |
| Martellus Bennett | 3 | x |
| Zach Miller | 4 | |
| Hunter Henry | 5 | x |
| Kyle Rudolph | 6 | |
| Jordan Reed | 7 | |
| Will Tye | 8 | |
| Garrett Celek | 9 | |
| Cameron Brate | 10 | x |
| Jack Doyle | 11 | |
| Delanie Walker | 12 | |
| Dennis Pitta | 13 | |
| Richard Rodgers | 14 | |
| Jason Witten | 15 | |
| Ryan Griffin | 16 | |
| Charles Clay | 17 | |
| Jesse James | 18 | |
| Clive Walford | 19 | |
| Gary Barnidge | 20 | |
| Jacob Tamme | 21 | |
| Adam Humphries | 22 | |
| C.J. Uzomah | 23 | |
| Rob Gronkowski | 24 | |
| Dwayne Allen | 25 | |
| Team Defense | Rank | Upside/Target |
| Buffalo Bills | 1 | |
| San Francisco 49ers | 2 | |
| Minnesota Vikings | 3 | x |
| Denver Broncos | 4 | |
| Miami Dolphins | 5 | |
| Carolina Panthers | 6 | |
| Pittsburgh Steelers | 7 | |
| Oakland Raiders | 8 | |
| Los Angeles Rams | 9 | x |
| Arizona Cardinals | 10 | |
| New England Patriots | 11 | x |
| Baltimore Ravens | 12 | |
| Chicago Bears | 13 | |
| Green Bay Packers | 14 | |
| Philadelphia Eagles | 15 | |
| Indianapolis Colts | 16 | |
| Houston Texans | 17 | |
| Cincinnati Bengals | 18 | |
| Tampa Bay Buccaneers | 19 | |
| Cleveland Browns | 20 |