| Rank | Player | Team | Pos | Opp |
| 1 | Blake Martinez | GB | LB | vs. DET |
| 2 | Joe Schobert | CLE | LB | vs. SEA |
| 3 | Cory Littleton | LAR | LB | vs. SF |
| 4 | Luke Kuechly | CAR | LB | at TB |
| 5 | Devin Bush | PIT | LB | at LAC |
| 6 | Bobby Wagner | SEA | LB | at CLE |
| 7 | Jordan Hicks | ARI | LB | vs. ATL |
| 8 | Deion Jones | ATL | LB | at ARI |
| 9 | Leighton Vander Esch | DAL | LB | at NYJ |
| 10 | John Johnson | LAR | S | vs. SF |
| 11 | Jamie Collins | NE | LB | vs. NYG |
| 12 | Lavonte David | TB | LB | vs. CAR |
| 13 | Shaq Thompson | CAR | LB | at TB |
| 14 | Vonn Bell | NO | S | at JAC |
| 15 | Danielle Hunter | MIN | DE | vs. PHI |
| 16 | Jaylon Smith | DAL | LB | at NYJ |
| 17 | Myles Garrett | CLE | DE | vs. SEA |
| 18 | Zach Cunningham | HOU | LB | at KC |
| 19 | J.J. Watt | HOU | DE | at KC |
| 20 | Jayon Brown | TEN | LB | at DEN |
| 21 | Joey Bosa | LAC | DE | vs. PIT |
| 22 | Demario Davis | NO | LB | at JAC |
| 23 | Budda Baker | ARI | S | vs. ATL |
| 24 | Eric Kendricks | MIN | LB | vs. PHI |
| 25 | Harrison Smith | MIN | S | vs. PHI |
| 26 | Jamal Adams | NYJ | S | vs. DAL |
| 27 | Landon Collins | WAS | S | at MIA |
| 28 | Shawn Williams | CIN | S | at BAL |
| 29 | Jabrill Peppers | NYG | S | at NE |
| 30 | Justin Reid | HOU | S | at KC |
| 31 | Kwon Alexander | SF | LB | at LAR |
| 32 | De'Vondre Campbell | ATL | LB | at ARI |
| 33 | Thomas Davis | LAC | LB | vs. PIT |
| 34 | Demarcus Lawrence | DAL | DE | at NYJ |
| 35 | Neville Hewitt | NYJ | LB | vs. DAL |
| 36 | Shaquil Barrett | TB | LB | vs. CAR |
| 37 | Terrell Edmunds | PIT | S | at LAC |
| 38 | Sam Hubbard | CIN | DE | at BAL |
| 39 | Cameron Jordan | NO | DE | at JAC |
| 40 | Antoine Bethea | NYG | S | at NE |
| 41 | Calais Campbell | JAC | DE | vs. NO |
| 42 | Todd Davis | DEN | LB | vs. TEN |
| 43 | Fred Warner | SF | LB | at LAR |
| 44 | Haason Reddick | ARI | LB | vs. ATL |
| 45 | Aaron Donald | LAR | DT | vs. SF |
| 46 | Nick Vigil | CIN | LB | at BAL |
| 47 | Minkah Fitzpatrick | PIT | S | at LAC |
| 48 | Cameron Heyward | PIT | DE | at LAC |
| 49 | Johnathan Joseph | HOU | CB | at KC |
| 50 | Myles Jack | JAC | LB | vs. NO |
| 51 | DeForest Buckner | SF | DT | at LAR |
| 52 | Carlos Dunlap | CIN | DE | at BAL |
| 53 | Devin White | TB | LB | vs. CAR |
| 54 | Montae Nicholson | WAS | S | at MIA |
| 55 | Jadeveon Clowney | SEA | DE | at CLE |
| 56 | Jordan Whitehead | TB | S | vs. CAR |
| 57 | T.J. Watt | PIT | LB | at LAC |
| 58 | Mario Addison | CAR | DE | at TB |
| 59 | Stephon Tuitt | PIT | DE | at LAC |
| 60 | Benardrick McKinney | HOU | LB | at KC |
