| Rank | Player | Team | Pos | Opp |
| 1 | Bobby Wagner | SEA | LB1 | vs. HOU |
| 2 | C.J. Mosley | BAL | LB2 | vs. MIA |
| 3 | Ryan Shazier | PIT | LB3 | at DET |
| 4 | Joey Bosa | LAC | DE1 | at NE |
| 5 | Reshad Jones | MIA | S1 | at BAL |
| 6 | Melvin Ingram | LAC | DE2 | at NE |
| 7 | Demarcus Lawrence | DAL | DE3 | at WAS |
| 8 | Kwon Alexander | TB | LB4 | vs. CAR |
| 9 | Zach Brown | WAS | LB5 | vs. DAL |
| 10 | Cameron Jordan | NO | DE4 | vs. CHI |
| 11 | Keanu Neal | ATL | S2 | at NYJ |
| 12 | Harrison Smith | MIN | S3 | at CLE |
| 13 | Everson Griffen | MIN | DE5 | at CLE |
| 14 | Christian Kirksey | CLE | LB6 | vs. MIN |
| 15 | Vontaze Burfict | CIN | LB7 | vs. IND |
| 16 | Khalil Mack | OAK | DE6 | at BUF |
| 17 | Trey Flowers | NE | DE7 | vs. LAC |
| 18 | Brandon Graham | PHI | DE8 | vs. SF |
| 19 | Danielle Hunter | MIN | DE9 | at CLE |
| 20 | Deion Jones | ATL | LB8 | at NYJ |
| 21 | Devin McCourty | NE | S4 | vs. LAC |
| 22 | Navorro Bowman | OAK | LB9 | at BUF |
| 23 | Karl Joseph | OAK | S5 | at BUF |
| 24 | Eric Kendricks | MIN | LB10 | at CLE |
| 25 | Ezekiel Ansah | DET | DE10 | vs. PIT |
| 26 | Carlos Dunlap | CIN | DE11 | vs. IND |
| 27 | Sean Lee | DAL | LB11 | at WAS |
| 28 | Demario Davis | NYJ | LB12 | vs. ATL |
| 29 | Akiem Hicks | CHI | DT1 | at NO |
| 30 | Myles Garrett | CLE | DE12 | vs. MIN |
| 31 | Danny Trevathan | CHI | LB13 | at NO |
| 32 | DeForest Buckner | SF | DE13 | at PHI |
| 33 | Jamie Collins | CLE | LB14 | vs. MIN |
| 34 | Jarrad Davis | DET | LB15 | vs. PIT |
| 35 | Benardrick McKinney | HOU | LB16 | at SEA |
| 36 | Jatavis Brown | LAC | LB17 | at NE |
| 37 | Lawrence Timmons | MIA | LB18 | at BAL |
| 38 | Reuben Foster | SF | LB19 | at PHI |
| 39 | Kenny Vaccaro | NO | S6 | vs. CHI |
| 40 | Cameron Wake | MIA | DE14 | at BAL |
| 41 | Craig Robertson | NO | LB20 | vs. CHI |
| 42 | Cameron Heyward | PIT | DE15 | at DET |
| 43 | Adrian Amos | CHI | S7 | at NO |
| 44 | Kyle Van Noy | NE | LB21 | vs. LAC |
| 45 | Lavonte David | TB | LB22 | vs. CAR |
| 46 | Glover Quin | DET | S8 | vs. PIT |
| 47 | Jahleel Addae | LAC | S9 | at NE |
| 48 | Frank Clark | SEA | DE16 | vs. HOU |
| 49 | Jordan Poyer | BUF | S10 | vs. OAK |
| 50 | Jaquiski Tartt | SF | S11 | at PHI |
| 51 | Fletcher Cox | PHI | DT2 | vs. SF |
| 52 | Tony Jefferson | BAL | S12 | vs. MIA |
| 53 | Ray-Ray Armstrong | SF | LB23 | at PHI |
| 54 | Muhammad Wilkerson | NYJ | DE17 | vs. ATL |
| 55 | Mason Foster | WAS | LB24 | vs. DAL |
| 56 | Geno Atkins | CIN | DT3 | vs. IND |
| 57 | Kiko Alonso | MIA | LB25 | at BAL |
| 58 | Nigel Bradham | PHI | LB26 | vs. SF |
| 59 | Nick Vigil | CIN | LB27 | vs. IND |
| 60 | Hayes Pullard | LAC | LB28 | at NE |
| 61 | Thomas Davis | CAR | LB29 | at TB |
| 62 | Leonard Williams | NYJ | DE18 | vs. ATL |
| 63 | Julius Peppers | CAR | DE19 | at TB |
| 64 | Darron Lee | NYJ | LB30 | vs. ATL |
| 65 | Matthias Farley | IND | S13 | at CIN |
| 66 | Lorenzo Alexander | BUF | LB31 | vs. OAK |
| 67 | Von Miller | DEN | LB32 | at KC |
| 68 | Eric Weddle | BAL | S14 | vs. MIA |
| 69 | Ndamukong Suh | MIA | DT4 | at BAL |
| 70 | Sean Davis | PIT | S15 | at DET |
| 71 | Alex Okafor | NO | DE20 | vs. CHI |
| 72 | Michael Bennett | SEA | DE21 | vs. HOU |
| 73 | K.J. Wright | SEA | LB33 | vs. HOU |
| 74 | Terrance Mitchell | KC | CB1 | vs. DEN |
| 75 | Micah Hyde | BUF | S16 | vs. OAK |
