Here's our fantasy football team defense rankings for week 10 of the NFL season. Be sure to read our WR Rankings, RB Rankings, QB Rankings, Kicker Rankings and TE Rankings.
| Rank | Team | Versus |
| 1 | Carolina Panthers | at TEN |
| 2 | Denver Broncos | vs. KC |
| 3 | St. Louis Rams | vs. CHI |
| 4 | New York Jets | vs. BUF |
| 5 | Green Bay Packers | vs. DET |
| 6 | Philadelphia Eagles | vs. MIA |
| 7 | Cincinnati Bengals | vs. HOU |
| 8 | New England Patriots | at NYG |
| 9 | Pittsburgh Steelers | vs. CLE |
| 10 | Seattle Seahawks | vs. ARI |
| 11 | Buffalo Bills | at NYJ |
| 12 | Arizona Cardinals | at SEA |
| 13 | Dallas Cowboys | at TB |
| 14 | Minnesota Vikings | at OAK |
| 15 | Oakland Raiders | vs. MIN |
| 16 | Tampa Bay Buccaneers | vs. DAL |
| 17 | Baltimore Ravens | vs. JAC |
| 18 | Miami Dolphins | at PHI |
| 19 | Kansas City Chiefs | at DEN |
| 20 | Cleveland Browns | at PIT |
| 21 | New Orleans Saints | at WAS |
| 22 | Jacksonville Jaguars | at BAL |
| 23 | Chicago Bears | at STL |
| 24 | Tennessee Titans | vs. CAR |
| 25 | New York Giants | vs. NE |
| 26 | Washington Redskins | vs. NO |
| 27 | Houston Texans | at CIN |
| 28 | Detroit Lions | at GB |
