The 2012 NFL season is here, we've all been waiting for week 1 since the end of the season last year. Here's our Week 1 Team Defense Fantasy Football Rankings! I like the Ravens the most, if you have them, lucky you! Waiver wire defenses are good for spot duty against weak teams. Look for the Seahawks and Saints to perform well in week 1.
| Rank | Team | Notes |
| 1 | Raven vs. Bengals | Bengals O-LINE is busted up and the Raven D-line is refreshed, its going to be a sack-o-rama! |
| 2 | Bears vs. Colts | Rookie QB versus historically sounds Bears Defense, no brainer week 1 pick. |
| 3 | Eagles vs. Browns | Browns fact elite corners and a pressure heavy d-line, Trent Richardson has also missed a ton of pre-season action. |
| 4 | Texans vs. Dolphins | Tannehill will have his hands full finding open WR against this blitx happy Texans D |
| 5 | Vikings vs. Jaguars | No MJD against a stack D-LINE, good luck Jennings. |
| 6 | Seahawks vs. Cardinals | Seahawks defense was solid last year, and is a big sleeper for me this year. No matter who the QB is look for a couple INT. |
| 7 | Lions vs. Rams | The Rams can pass protect and that's what they'll have to figure out in the 2nd quarter. |
| 8 | Saints vs. Redskins | Saints won't be able to stop the run, to bad the Skins will have to pass to catchup in the 2nd QTR. Doesn't bode well for a rookie QB. |
| 9 | Jets vs. Bills | Historically a very sound defense, they'll have to play strong for the team to compete, and they know this! |
| 10 | Pats vs. Titans | Locker is a "lock" for two picks while trying to play catch-up in week 1. |
| 11 | Giants vs. Cowboys | The Cowboy will be off to a slow start with Witten sidelined and Austin out of sync with Romo.. |
| 12 | Bill vs. Jets | It's the Jets, need I say more? This one should be a low scoring affair. |
| 13 | Bengals vs. Ravens | |
| 14 | Steelers vs. Broncos | Manning first test is a tough one, but he'll dink and dunk his way, or will he? |
| 15 | Broncos vs. Steelers | |
| 16 | Cowboys vs. Giants | |
| 17 | 49's vs. Packers | |
| 18 | Cardinals vs. Seahawks | Rookie QB who I really don't believe in, would rank Cardinals higher if they had a better fantasy football Defense |
| 19 | Chiefs vs. Falcons | |
| 20 | Falcons vs. Chiefs |
