Both Kamara (NO) and Johnson (AZ) have multiple injuries and may or may not play this week. But the more they play, the more the chances increase they will get hurt further. If Chase Edmonds (AZ) and Latavius Murray (NO) are available in your league now is the time to grab them. We've seen this before where a running back starts to break down and carries multiple injuries into games. At times they end up sitting multiple weeks to heal and these two are prime candidates to become fantasy relevant in the near future. Good luck this week guys and gals.
| Rank | Running Backs | Team | Opp |
| 1 | Leonard Fournette | JAC | at CIN |
| 2 | Saquon Barkley | NYG | vs. ARI |
| 3 | Dalvin Cook | MIN | at DET |
| 4 | Chris Carson | SEA | vs. BAL |
| 5 | Ezekiel Elliott | DAL | vs. PHI |
| 6 | Le'Veon Bell | NYJ | vs. NE |
| 7 | David Johnson | ARI | at NYG |
| 8 | Aaron Jones | GB | vs. OAK |
| 9 | Marlon Mack | IND | vs. HOU |
| 10 | Phillip Lindsay | DEN | vs. KC |
| 11 | Josh Jacobs | OAK | at GB |
| 12 | Alvin Kamara | NO | at CHI |
| 13 | Derrick Henry | TEN | vs. LAC |
| 14 | Sony Michel | NE | at NYJ |
| 15 | Mark Ingram | BAL | at SEA |
| 16 | Kerryon Johnson | DET | vs. MIN |
| 17 | Devonta Freeman | ATL | vs. LAR |
| 18 | Todd Gurley | LAR | at ATL |
| 19 | Joe Mixon | CIN | vs. JAC |
| 20 | Tevin Coleman | SF | at WAS |
| 21 | Melvin Gordon | LAC | at TEN |
| 22 | Royce Freeman | DEN | vs. KC |
| 23 | David Montgomery | CHI | vs. NO |
| 24 | Matt Breida | SF | at WAS |
| 25 | Austin Ekeler | LAC | at TEN |
| 26 | Carlos Hyde | HOU | at IND |
| 27 | Frank Gore | BUF | vs. MIA |
| 28 | LeSean McCoy | KC | at DEN |
| 29 | Devin Singletary | BUF | vs. MIA |
| 30 | Adrian Peterson | WAS | vs. SF |
| 31 | James White | NE | at NYJ |
| 32 | Damien Williams | KC | at DEN |
| 33 | Jordan Howard | PHI | at DAL |
| 34 | Jamaal Williams | GB | vs. OAK |
| 35 | Miles Sanders | PHI | at DAL |
| 36 | Latavius Murray | NO | at CHI |
| 37 | Kenyan Drake | MIA | at BUF |
| 38 | Malcolm Brown | LAR | at ATL |
| 39 | Duke Johnson | HOU | at IND |
| 40 | Tarik Cohen | CHI | vs. NO |
| 41 | Chase Edmonds | ARI | at NYG |
| 42 | Ito Smith | ATL | vs. LAR |
| 43 | Gus Edwards | BAL | at SEA |
| 44 | Alexander Mattison | MIN | at DET |
| 45 | Giovani Bernard | CIN | vs. JAC |
| 46 | Mark Walton | MIA | at BUF |
| 47 | Darrell Henderson | LAR | at ATL |
| 48 | Nyheim Hines | IND | vs. HOU |
| 49 | Wendell Smallwood | WAS | vs. SF |
| 50 | Raheem Mostert | SF | at WAS |
